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Centro Hospitalar e Universitário de Coimbra

Centro Hospitalar e Universitário de Coimbra

CHUC - Innovation & Research

The Centro Hospitalar e Universitário de Coimbra (CHUC) offers specialized care on all areas of medicine, from prenatal to elderly care, covering the entire life cycle of the person and family. Clinical and translational research is a critical component of our mission, and one of our priorities.

The Centro Hospitalar e Universitário de Coimbra (CHUC) is the largest healthcare institution in Portugal. It includes 2 general hospitals (Hospitais da Universidade de Coimbra and Hospital Geral), a paediatric hospital (Hospital Pediátrico de Coimbra), two maternities (Maternidade Bissaya Barreto and Maternidade Daniel de Matos) and a psychiatric hospital (Hospital Psiquiátrico Sobral Cid). We offer specialized care on all areas of medicine, from prenatal to elderly care, covering the entire life cycle of the person and family.

CHUC acts both as proximity centre for the population of the Coimbra District as well as reference tertiary centre for the Centro region of Portugal with about 2 million inhabitants. In 2021, CHUC includes 18 accredited reference centres (the largest number in Portugal) and is a partner in 10 European Reference Networks (highest number in Iberian Peninsula, along with Vall D’Hebron Hospital in Barcelona).

Our main purpose is to provide excellent person-centred medical care in association with pre and postgraduate education and the best biomedical research. Clinical and translational research is a critical component of our mission, and one of our priorities. The Unit of Innovation and Development (UID) promotes and manages research activities at CHUC. The unit includes a management board, secretarial support, project managers and study coordinators (currently 8), which support researchers in the attraction, submission, and development of clinical and translational studies. The Unit’s activities take place on all CHUC hospitals, while a specific building is used for headquarters.

In 2019, there were 126 active trials in CHUC, with 826 patients included. We aim to increase this activity by investing in new strategic units such as Ophthalmology and Paediatrics. CHUC is a national reference on healthcare innovation projects, due to the strong commitment of our professionals. By the end of 2020 CHUC was a partner on 21 internationally funded projects. The areas with more expression on these projects are neurological and cardiovascular diseases, but other areas such as anaesthesiology, pulmonary diseases, vision and metabolic diseases are also included.

Our institution has a solid connection to the University of Coimbra (UC) and the Faculty of Medicine (FMUC) since its inception. CHUC and UC joined for a Consortium named Centro Académico e Clínico de Coimbra (CACC), that aims to create synergies and strategic partnerships, introduce innovative programs and promote a culture of clinical and scientific excellency as well as quality of care. This consortium (Coimbra Health) is a member of the M8 Alliance of Academic Health Centers, Universities and National Academies, which aims for global health improvement and development of science-based solutions to global health challenges.

Year

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General Indicators
No. of active clinical studies by study type
  • 95
    Active Clinical Trials
  • 282
    Active Non-Interventional Studies
No. of initiated clinical studies by study type
  • 33
    Clinical Trials initiated
  • 282
    Non-Interventional Studies initiated
No. of active non-interventional clinical studies by therapeutic area
No. of active non-interventional clinical studies by sponsor type
No. of active Clinical trials by sponsor type
No. of active clinical trials per phase
No. of active clinical trials by trial object
No. of active clinical trials by therapeutic area
  • 1314
    No. of publications in indexed journals - last 5 full years
  • 80
    No. of health professionals with specific training in GCP (Good Clinical Practices)
Global Capacity Indicators
  • 1557
    No. of available beds in the institution
  • 1653
    No. of Physicians in the Institution
  • 3299
    No. of Nurses in the Institution
  • 60
    No. of Pharmacists in the Institution
  • 500 thousand
    No. of Inhabitants covered by the institution
    As a reference centre: 1.8 million
HR Indicators Allocated to Research
Total number of people dedicated to clinical research in the institution
  • 80
    Researchers
  • 11
    Managers, Administrative, Legal and Financial
  • 8
    Study coordinators
  • 11
    Nurses
  • 5
    Pharmacists
Efficiency Indicators
  • 609
    Total number of participants recruited for clinical trials and interventional clinical studies of medical devices
  • 77
    Patient recruitment rate in clinical trials and interventional clinical studies of medical devices
  • -
    Average time to first patient recruitment in clinical trials and interventional clinical studies of medical devices
  • -
    Average time between submission and approval of the Financial Contract in clinical trials and interventional clinical studies of medical devices
General Indicators
No. of active clinical studies by study type
  • 84
    Active Clinical Trials
  • 244
    Active Non-Interventional Studies
No. of initiated clinical studies by study type
  • 35
    Clinical Trials initiated
  • 244
    Non-Interventional Studies initiated
No. of active non-interventional clinical studies by therapeutic area
No. of active non-interventional clinical studies by sponsor type
No. of active Clinical trials by sponsor type
No. of active clinical trials per phase
No. of active clinical trials by trial object
No. of active clinical trials by therapeutic area
  • 1132
    No. of publications in indexed journals - last 5 full years
  • 80
    No. of health professionals with specific training in GCP (Good Clinical Practices)
Global Capacity Indicators
  • 1415
    No. of available beds in the institution
  • 1632
    No. of Physicians in the Institution
  • 3229
    No. of Nurses in the Institution
  • 61
    No. of Pharmacists in the Institution
  • 432 thousand
    No. of Inhabitants covered by the institution
HR Indicators Allocated to Research
Total number of people dedicated to clinical research in the institution
  • 80
    Researchers
  • 11
    Managers, Administrative, Legal and Financial
  • 8
    Study coordinators
  • 11
    Nurses
  • 5
    Pharmacists
Efficiency Indicators
  • 657
    Total number of participants recruited for clinical trials and interventional clinical studies of medical devices
  • 77%
    Patient recruitment rate in clinical trials and interventional clinical studies of medical devices
  • 0 days
    Average time to first patient recruitment in clinical trials and interventional clinical studies of medical devices
  • 168 days
    Average time between submission and approval of the Financial Contract in clinical trials and interventional clinical studies of medical devices

Clinical Research Areas of interest

Clinical Research Areas of interest

  • Cardiovascular disease: heart failure, pulmonary hypertension, coronary disease, stroke
  • Neurological disease: dementia, demyelinating diseases
  • Endocrine and metabolic diseases
  • Neoplasm: lung cancer, hemato-oncology, urologic oncology
  • Pediatric diseases: autism, pediatric oncology
  • Eye diseases, retinal disease
  • Respiratory disease: asthma, COPD, interstitial lung disease
  • Auto-immune disease
  • Intestinal inflammatory disease
  • Gynecologic disease
  • Renal diseases
  • Skin diseases: melanoma

Gallery

Hospitais da Universidade de Coimbra (CHUC General Hospital)

Hospitais da Universidade de Coimbra (CHUC General Hospital)

One of CHUC's General Hospitals
Hospital Geral (CHUC General Hospital)

Hospital Geral (CHUC General Hospital)

One of CHUC's General Hospitals
Pediatric Hospital

Pediatric Hospital

CHUC's Paediatric Unit
Bissaya Barreto Maternity

Bissaya Barreto Maternity

One of CHUC's maternities
Daniel de Matos Maternity

Daniel de Matos Maternity

One of CHUC's maternities
Sobral Cid Psychiatric Hospital

Sobral Cid Psychiatric Hospital

CHUC's psychiatric hospital

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